Femoral Nerve Anatomy

The femoral nerve stands as one of the most significant peripheral nerves in the lower limb, playing a crucial role in both motor and sensory functions of the lower limb. As medical professionals, understanding its detailed anatomy, course, branches, and functions is essential for accurate diagnosis and treatment of lower limb pathologies. This article provides an in-depth examination of femoral nerve anatomy with particular emphasis on its course, branches, and functional significance.
Femoral Nerve Anatomy
Origin and Formation
The femoral nerve originates from the lumbar plexus, specifically from the posterior divisions of the ventral rami of the L2, L3, and L4 spinal nerves. This nerve emerges from the lateral border of the psoas major muscle, where it traverses the pelvis and enters the thigh by passing deep to the inguinal ligament. Its location lateral to the femoral artery within the femoral sheath makes it a critical anatomical landmark during surgical approaches to the anterior thigh.
See Also: Lumbar Plexus Anatomy

Femoral Nerve Course
The femoral nerve course begins within the substance of the psoas major muscle, where the nerve roots combine to form the main trunk. As it descends, the nerve travels through the iliac fossa between the psoas and iliacus muscles, covered by the iliac fascia. This relationship is clinically significant as psoas abscesses or hematomas can potentially compress the nerve at this point.
Upon reaching the inguinal ligament, the femoral nerve course continues as it passes beneath this structure, entering the femoral triangle. Within this triangle, the nerve lies lateral to the femoral artery and outside the femoral sheath that encloses the femoral vessels. This topographical relationship—remembered by the mnemonic NAVEL (from lateral to medial: femoral Nerve, femoral Artery, femoral Vein, Empty space, Lymphatics)—is essential knowledge for clinicians performing femoral nerve blocks or approaching the femoral vessels.
Immediately after entering the thigh, the femoral nerve course divides into anterior and posterior divisions. This bifurcation typically occurs approximately 3-4 cm distal to the inguinal ligament. The anterior division primarily provides cutaneous innervation, while the posterior division supplies motor function to the quadriceps muscles and sensory innervation to the medial aspect of the lower leg via the saphenous nerve.

Femoral Nerve Branches
The femoral nerve branches can be classified into muscular and cutaneous components. Understanding these branches and their distributions is crucial for interpreting clinical presentations of femoral neuropathy.
The muscular femoral nerve branches supply the anterior compartment muscles of the thigh. These include:
- The iliopsoas muscle, which receives innervation before the nerve passes beneath the inguinal ligament.
- The pectineus muscle, which typically receives dual innervation from both the femoral nerve and occasionally the obturator nerve.
- The quadriceps femoris muscle group, consisting of four powerful knee extensors: rectus femoris, vastus lateralis, vastus medialis, and vastus intermedius.
- The sartorius muscle, which functions to flex, abduct, and laterally rotate the hip while flexing the knee.
The cutaneous femoral nerve branches provide sensory innervation to the anterior and medial thigh, medial leg, and foot. These include:
The anterior cutaneous branches of the thigh, which pierce the fascia lata to supply the skin over the anterior and medial thigh down to the knee. The medial cutaneous nerve of the thigh, which divides into anterior and posterior branches to supply the medial aspect of the thigh. The saphenous nerve, which is the largest and longest cutaneous branch. It accompanies the femoral artery through the adductor canal, then continues with the great saphenous vein to provide sensation to the medial aspect of the leg and foot.

Femoral Nerve Function
Femoral nerve function encompasses both motor and sensory components essential for lower limb movement and sensation. Understanding these functions is paramount for accurately diagnosing and managing femoral nerve pathologies.
The motor function of the femoral nerve primarily involves hip flexion and knee extension. The nerve innervates the powerful quadriceps femoris muscle group, which serves as the primary knee extensor—an action essential for walking, climbing stairs, rising from a seated position, and maintaining an upright posture. The sartorius muscle, also supplied by the femoral nerve, contributes to hip flexion, abduction, and lateral rotation, playing a role in movements such as crossing the legs.
The sensory function of the femoral nerve includes proprioception from the hip and knee joints and cutaneous sensation from the anterior thigh and medial leg. The nerve provides articular branches to the hip and knee joints, contributing to joint position sense and facilitating coordinated movement. Through its cutaneous branches, particularly the saphenous nerve, it supplies sensation to the skin over the anteromedial thigh, medial leg, and medial border of the foot up to the medial malleolus.
Clinical Significance
Femoral nerve injuries or neuropathies can result in significant functional impairment. Damage to the nerve can occur from direct trauma, pelvic fractures, iatrogenic injury during surgery, compression from hematomas (particularly in patients on anticoagulation therapy), or metabolic causes such as diabetic neuropathy.
Clinical manifestations of femoral nerve dysfunction typically include weakness or paralysis of the quadriceps muscles, resulting in difficulty extending the knee and potential instability while walking. This often presents as a characteristic “steppage gait” where the patient must lift the affected limb higher to clear the foot from the ground during swing phase. Sensory deficits manifest as numbness or paresthesia over the anterior thigh and medial aspect of the leg.
Clinicians assess femoral nerve function by testing quadriceps strength through knee extension against resistance, evaluating the patellar reflex (L2-L4), and examining sensation over the anteromedial thigh and medial leg. Electromyography and nerve conduction studies provide valuable diagnostic information regarding the extent and location of nerve damage.
Conclusion
The femoral nerve represents a critical neural structure with complex anatomical relationships and essential functional roles in lower limb movement and sensation. Its course from the lumbar plexus through the pelvis and into the thigh, its diverse branches to muscles and cutaneous territories, and its functions in knee extension and sensory perception make it a subject of considerable importance for medical professionals dealing with lower limb pathologies. A thorough understanding of femoral nerve anatomy serves as the foundation for accurate diagnosis, effective treatment, and optimal outcomes in patients with femoral nerve disorders.
Resources
- Drake RL, Vogl AW, Mitchell AWM. Gray’s Anatomy for Students. 4th ed. Philadelphia, PA: Elsevier; 2020. https://www.elsevier.com/books/grays-anatomy-for-students/drake/978-0-323-39304-1
- Moore KL, Dalley AF, Agur AMR. Clinically Oriented Anatomy. 8th ed. Philadelphia, PA: Wolters Kluwer; 2018.
- Netter FH. Atlas of Human Anatomy. 7th ed. Philadelphia, PA: Elsevier; 2019. https://www.elsevier.com/books/atlas-of-human-anatomy/netter/978-0-323-39322-5
- Standring S. Gray’s Anatomy: The Anatomical Basis of Clinical Practice. 42nd ed. Edinburgh: Elsevier; 2020. https://www.elsevier.com/books/grays-anatomy/standring/978-0-7020-7705-0
- Tubbs RS, Rizk E, Shoja MM, Loukas M. Nerves and Nerve Injuries: Vol 1: History, Embryology, Anatomy, Imaging, and Diagnostics. London: Academic Press; 2015. https://www.elsevier.com/books/nerves-and-nerve-injuries/tubbs/978-0-12-410390-0
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